Gut Bacteria Drive Autoimmune Disease


The Enemy Within

Generally, bacteria can found in the human body they also live in our intestine. They can trigger an autoimmune response. A new study of new yale has shown it. Recently The researchers also found that the autoimmune reaction can suppress. It can suppress by the vaccine designed to target the bacteria.

The reserves they said. the bacterias living in the intestine linked to many diseases. That includes autoimmune conditions characterized. By immune system attack of healthy tissue. as they shed light on this link. Now the researchers have focused on Enterococcus gallinarum.

This is a bacterium they discovered is able to “translocate” outside of the gut to lymph nodes. That also prevails in the liver and spleen. As in the case of mice. The researchers observed that in tissues. Outside the gut, E. Gallinarum initiated the production. as the antibodies and inflammation — hallmarks of the autoimmune response.

Researchers confirmed the same mechanism. of inflammation in cultured liver cells of healthy people.

This occurs bacterium in livers of patients with autoimmune disease.  There are further experiments. Have done the research team found. that they could suppress autoimmunity in mice with an antibiotic. a vaccine aimed at E. Which is also known as gallinarum.

The researchers were able to suppress the growth of the bacteria in the muscle tissues and blunt its effects on the immune system.  Martin Kriegel is a senior author. Who said, When we blocked the pathway leading to inflammation, we could reverse the effect of this bug on autoimmunity”.  he also added The vaccine against E.

Gallinarum was a specific approach. As for vaccinations against other bacteria. we examined investigated did not prevent mortality and autoimmunity,” he noted. The vaccine delivered through injection in muscle. To avoid targeting other bacteria that stayed in the gut. as M.A. Kriegel & S. Manfredo-Vieira have a patent which related to the discovery.